Compared Dexmedetomidine and Fentanyl on Sensory-Motor Block in Unilateral Intrathecal Anesthesia of Lower-limbs Orthopedic Surgeries: A Randomized Duble-blind Trials

Background: One of the alternatives for lower-limb orthopedic surgery is spinal anesthesia. It can affect hemodynamic status and cause prolonged motor sensory blocks, as well urinary retention, which are less common in unilateral technique. Different drugs used to improve quality block reduce its complications. Dexmedetomidine, a selective alpha-2 adrenergic receptor agonist, fentanyl, an opioid medication, could administration adjuvant increase intrathecal quality. Hence, this study aimed compare anesthesia with bupivacaine/dexmedetomidine (BD) bupivacaine/fentanyl (BF) regimes on sensory-motor among patients surgeries. Materials Method: This randomized, double-blind clinical trial was performed 36 who underwent surgeries Qaem Hospital, Mashhad, Iran. The were randomly divided into two groups. Patients received 5.7 mg hyperbaric bupivacaine 0.5% plus 10 µg fentanyl (BF group) or 5 dexmedetomidine (BD administered inducing investigators responsible data collection not awarded from allocation level, duration, postoperative analgesia, complications recorded compared between Results: No significant difference observed groups changes (i.e., systolic diastolic blood pressure heart rate) before after blockage (P˃0.05). Also, there no level anesthesia-related BF BD Conclusion: In whom use opioids contraindicated, be considered appropriate alternative.